Steroid-responsive encephalopathy associated with autoimmune thyroiditis

Ocular adverse reactions occurring in 5%-15% of patients treated with loteprednol etabonate ophthalmic suspension (%-%) in clinical studies included abnormal vision/blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, injection, and photophobia. Other ocular adverse reactions occurring in less than 5% of patients include conjunctivitis, corneal abnormalities, eyelid erythema, keratoconjunctivitis, ocular irritation/pain/discomfort, papillae, and uveitis. Some of these events were similar to the underlying ocular disease being studied.

Peripheral Light Spectrum (PLS)
Peripheral Light Spectrum (PLS) is a temporary phenomenon whereby patients report the perception of a spoke-like spectrum of light in
the periphery of their vision. PLS has no clinical examination findings and no effect on visual acuity; however the potential diffractive
effects may be bothersome to some patients. Reported in only % of cases, the onset of symptoms occurs during the immediate
postoperative period, and typically resolves within three months but may be slightly persistent in rare cases. The visual impact of PLS is
clinically inconsequential for the vast majority of patients.

A diagnosis is normally made on the basis of first excluding other causes of spinal pain (like bone or soft tissue infections, immune-mediated joint disease, infections) by obtaining a blood sample and performing radiographs. Then, cerebro-spinal fluid (CSF) analysis is performed by obtaining a sample of CSF from the neck or lower spine (or both) in a sterile manner under general anaesthesia . Your pet will have dedicated one-to-one care during their CSF tap by one of our nurses from the prep nursing team who are trained and experienced in anaesthesia and sedation . The demonstration of inflammation and the presence of a specific type of inflammatory cell facilitate a presumptive diagnosis. Although infection is very unlikely, we will normally run a panel of various blood and urine tests to exclude this possibility.

The problem usually develops in young adults. Signs include fever, stiff neck, hyper-reactivity to touch, and reduced mobility due to marked stiffness. It can be acute or chronic. The cause is not well understood, but because it responds to steroid therapy, it is likely an autoimmune condition. Autoimmune problems occur when the body sees itself as foreign and mounts a reaction. There is the possibility that infectious agents can trigger this reactivity. Steroid medications have anti-inflammatory action, and at high doses, inhibit the immune system.

Steroid-responsive encephalopathy associated with autoimmune thyroiditis

steroid-responsive encephalopathy associated with autoimmune thyroiditis

The problem usually develops in young adults. Signs include fever, stiff neck, hyper-reactivity to touch, and reduced mobility due to marked stiffness. It can be acute or chronic. The cause is not well understood, but because it responds to steroid therapy, it is likely an autoimmune condition. Autoimmune problems occur when the body sees itself as foreign and mounts a reaction. There is the possibility that infectious agents can trigger this reactivity. Steroid medications have anti-inflammatory action, and at high doses, inhibit the immune system.

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