Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( http:///c4Rm4p ) for more information if you do not have access to a take-back program.
This product has a greater ability to produce adrenal suppression than does diflorasone diacetate ointment USP, %. At 30 g per day (applied as 15 g twice daily) diflorasone diacetate cream USP, % was shown to cause inhibition of the HPA axis in one of two patients following application for one week to psoriatic skin. At 15 g per day (applied as g twice daily) diflorasone diacetate cream USP, % was shown to cause mild inhibition of the HPA axis in one of five patients following application for one week to diseased skin (psoriasis or atopic dermatitis). These effects were reversible upon discontinuation of treatment. By comparison, diflorasone diacetate ointment USP, % did not produce significant HPA axis suppression when used in divided doses at 30 g per day for one week in patients with psoriasis or atopic dermatitis.
Zinc Sprays Mass Marketed as Psoriasis Treatments Starting in 1999, there have been several agressive marketing campaigns for topical zinc products such as Skin-Plaque, Skin-Zinc, SkinZinc, Acadia Skin Care , and others. These appear to sprout up around the Scarborough, Maine area. That is coincidentally where DermaZinc is produced. Questions to a telemarketer for the Skin-Zinc product gave hints that Jeff Kral and ( whois ) is the marketing company behind the SkinZinc campaign. The ads have appeared in USA Today, many newspapers, radio spots, and now half hour infomercials in many cities. They never list the ingredients or price, but they often make claims that the product is patented and FDA approved. This is a deception, because no such products are allowed to claim FDA approval, and makers of topical zinc pyrithione products are in fact specifically banned from making psoriasis treatment claims. [See April 9, 2003 FDA Skin-Zinc Warning Letter .] It is presumed that they are without any added steroids, but the promoters are clearly operating outside ethical boundaries and it's hard to guess how far they are willing to go to make a buck. Note that SkinZinc is marketed using the same before/after photos as DermaZinc with clobetasol . The SkinZinc makers state the ingredients as % Zinc Pyrithione, Water, Glycerine, Propylene Glycol, with added willowherb, aloe, and quaternium 15. Many people have reported returning these zinc products as ineffective, with almost no reports of success (except by shills) either publicly or privately. The $15 shipping fee isn't refundable, and Selfworx suggests insuring and package-tracking any returned products, or they will not be responsible for providing a refund. Some collected References and Links: